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ea0063gp189 | Adrenal and Neuroendocrine - Clinical | ECE2019

Plasma renin concentration is associated with cardiac function and morphology in primary adrenal insufficiency

Wolf Peter , Beiglbock Hannes , Fellinger Paul , Pfleger Lorenz , Aschauer Stefan , Gessl Alois , Trattnig Siegfried , Kautzky-Willer Alexandra , Luger Anton , Winhofer Yvonne , Krssak Martin , Krebs Michael

Background: Despite adequate glucocorticoid (GC) and mineralocorticoid (MC) replacement therapy, primary adrenal insufficiency (AI) is associated with an increased mortality, mainly due to cardiovascular disease. The role of MC replacement is not known. Therefore we assessed whether renin concentrations during routine GC and MC substitution therapy are associated with cardiac function and morphology.Methods: 17 patients with AI underwent magnetic resonan...

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Plasma renin concentration is associated with cardiac function and morphology in primary adrenal insufficiency

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